N-Acetyl Cysteine (NAC): Uses, Dosage, Side Effects & More - Ojus Life

N-Acetyl Cysteine (NAC): Uses, Dosage, Side Effects & More

Dr Anita Nischal


N-acetylcysteine (NAC) is a plant antioxidant organically discovered in onions and is a pioneer of glutathione. N-acetylcysteine is a herald to the amino acid L-cysteine and therefore the antioxidant glutathione (GSH).

NAC has been used as a medicine ever since the 1960s and is enumerated on the World Health Organization (WHO) Model List of Crucial Medicines as a cure for poisonings. Also, NAC n-acetylcysteine is a dominant antioxidant and suggested as a prospective healing preference for various disorders stemming from the generation of free oxygen radicals.

In addition, it is a safeguarded and endured mucolytic medication that develops persistent mucous discharges. Besides, it is a great protector against numerous diseases in direct action or a blend with some other medications.

Moreover, NAC is also employed in food supplements and cosmetics. Because of its ample use, there are estimates that the NAC global market will expand in the next five years. Hence, here we give a balanced view of more uses of NAC supplement, NAC dosage, and side-effects of NAC.

Uses of NAC Supplement

NAC n-acetylcysteine is the supplement type of the amino acid cysteine. It is suggested that taking N-acetylcysteine supplements can safeguard alongside a surplus of health troubles such as respiratory diseases, certain cancers, liver disease, psychiatric disorders, diabetes, and chemical dependency.

NAC vitamin facilitates vital biological functions by connecting with two other amino acids—glutamine and glycine—to produce glutathione. Further, glutathione is a powerful antioxidant that plays a major role in controlling several cellular activities and supports the immune system. Also, glutathione improves and neutralizes free radicals that harm cells and tissues at the molecular level.


Recommended Dosage for N-Acetyl Cysteine

The prescribed NAC Dosages- should be given as follows:

Age Group Recommended Dosage of NAC
Adult 10% or 20% solution by nebulization
Children (1-11 months) 1-2 mL of 20% solution by nebulization
Children (1-11 years) 3-5 mL of 20% solution or 6-10 mL of 10% solution by nebulization
Children (Over 12 years) 5-10 mL of 10% or 20% solution by nebulization


Doses of up to 1,200 mg per day have been used carefully in adults. As a rule of thumb, you must never take more than the recommended NAC vitamin dosage listed on the product label.


Only amino acid supplements, like NAC N-acetylcysteine, are safest when taken on an empty stomach. The absorption of amino acids can be influenced by the foods you eat.

N-acetylcysteine NAC vitamin can be stowed at room temperature in a cool, dry room. Also, prevent taking any NAC supplements that have expired, are discolored or show indications of deterioration.

NAC Dosage for Bronchitis

NAC can mitigate the symptoms of respiratory illnesses by behaving as an antioxidant and expectorant, relaxing mucus in your air passageways. As an antioxidant, the NAC vitamin helps refill glutathione levels in your lungs and lessens inflammation in your bronchial tubes and lung tissue.

The 600 mg of NAC twice a day substantially enhanced lung function and reduced the symptoms of COPD. Those with chronic bronchitis can similarly heal with NAC.

Bronchitis happens when the mucous membranes in your lungs’ bronchial passageways become swollen and shut off airways to your lungs. Thus, by thinning mucus in your bronchial tubes and increasing glutathione levels, NAC may support decreasing the seriousness and occurrence of wheezing, coughing and respiratory attacks.

NAC Dosage for PCOS

Polycystic ovary syndrome (PCOS) is widespread endocrine glands-related diseases influencing 5-10% of reproductive-age women. This disease is deemed the most common root of anovulatory infertility. PCOS is also linked with pregnancy problems such as recurrent pregnancy loss.

NAC is a mucolytic medication with insulin-sensitizing properties that has been used effectively as a backing therapy in areas with CC-resistant PCOS. A mixture of CC and NAC noticeably boosted both ovulation and pregnancy rates in women. NAC supplement use has several biological impacts, two of which are possibly and associated with pregnancy rate development.

NAC Dosage for Liver Support

NAC supports detoxification to avert or lessen kidney and liver damage. NAC plays an essential role in your body’s detoxification procedure.

Doctors frequently give intravenous (IV) NAC vitamins to people with an acetaminophen overdose to stop or reduce kidney and liver damage. NAC also has functions for other liver diseases anticipated by its antioxidant and anti-inflammatory advantages.

NAC Dosage for Endometriosis

Endometriosis affects 1 in 10 women in America, and probably many more. It is a disorder where tissue that usually lines the uterus—called the endometrium—develops in other parts of the body where they are not supposed to be. Most usually, these tissues grow in the abdominal cavity, where they can land on the intestinal lining, ovaries, and fallopian tubes.

Furthermore, this tissue is prompted by the same hormonal changes that cause your period to come each month, affecting this tissue to bleed as well. Standard medicine has not essentially discovered how to best treat endometriosis.

So, NAC is used, which focuses on symptom relief. And the NAC supplement used can provide relief of pain and decrease the symptoms of the same. NAC can relieve symptoms of mild to moderate pain but also have prospective side effects.

Side Effects of N-Acetyl Cysteine

Common side effects of NAC n-acetylcysteine comprise:

  • Bronchospasm
  • Disagreeable odor
  • Drowsiness
  • Fever
  • Coughing up blood
  • Increased volume of bronchial secretions
  • Irritation of tracheal or bronchial tract
  • Nausea
  • Runny or stuffy nose
  • Swelling and sores inside the mouth
  • Vomiting
  • Clamminess
  • Wheezing
  • Shortness of breath

Severe side effects of NAC dosage consist of:

  • Chest tightness
  • Bronchoconstriction
  • Bleeding


The amino acid supplements, like N-acetylcysteine, are advised to be taken on an empty stomach. So, you must take it in the morning before your meals.


NAC substantially lessened the symptoms of trichotillomania. Around 56% percent of people reported that they feel better after taking NAC. A substantial increase was primarily noted after 9 weeks of taking NAC supplement regularly.


NAC is vital for making the powerful Antioxidant Glutathione, enhance Psychiatric Disorders & Addictive Behavior, helps with Detoxification and prevent Kidney and Liver damage. Besides, the NAC vitamin helps relieve symptoms of Respiratory conditions and improves brain health by controlling Glutamate.


The advised daily NAC supplement dosage is 600–1,800 mg (44, 45). NAC can be processed as an IV or consumed orally, as an aerosol spray or in liquid or powder tablet form.


The markets are flooded with the supply of NAC, but one must purchase from authentic sources. OjusLife delivers herbal and natural NAC vitamin which includes all herbal ingredients and is a non-GMO & gluten-free product. OjusLife’s NAC comprises liver-supportive ingredients that are scientifically demonstrated to support good liver health. Furthermore, NAC is an herbal-based plant formula that contains many top-quality ingredients and makes this product the best vitamins for bronchitis.


Apart from relieving COPD and bronchitis, NAC may enhance other lung and respiratory tract illnesses like cystic fibrosis, asthma, and pulmonary fibrosis, as well as signs of nasal and sinus congestion anticipated to allergies or infections.